Body Magnetic Resonance Research Group
The goal of our research is to develop novel Magnetic Resonance Imaging (MRI) methods with an emphasis on the extraction of quantitative imaging biomarkers. Our group has an expertise on developing MRI acquisition, reconstruction and signal modeling techniques for measuring tissue diffusion, relaxation, magnetic susceptibility and fat content properties. The developed methods are being translated into clinical studies for improving the diagnosis, the therapy monitoring, and the understanding of disease pathophysiology in the diseases of the musculoskeletal system (e.g. osteoporosis, neuropathies, neuromuscular diseases), in metabolic dysfunction (e.g. obesity, diabetes, cancer cachexia) and in body oncology (e.g. abdominal and musculoskeletal tumors).
Christof Böhm, M.Sc.
Dr. med. Dr. dent. Egon Burian
Elizabeth Huaroc, M.Sc.
Dr. med. Daniela Junker
Sophia Kronthaler, M.Sc.
Sean McTavish, M.Sc.
Dr. rer. nat. Stefan Ruschke
Dominik Weidlich, M.Sc.
Dr. rer. nat. Mingming Wu
Mark Zamskiy, B.Sc.
Yupeng Zhao, B.Sc.
Christoph Zöllner, M.Sc.
Veronica Bodek, MHBA
PD Dr. rer. nat. Carl Ganter
Anh Van, PhD
Kilian Weiss, PhD
External CollaboratorsDepartment of Radiology and Biomedical Imaging, University of California, San Francisco
Philips Research Laboratory, Hamburg
Department of Computing, Imperial College London
Department of Radiology, University of Texas Southwestern Medical Center
Department of Electrical Engineering and Computer Sciences, University of California, Berkeley
Institute for Diabetes and Cancer, Helmholtz Center Munich
Department of Radiology, Leiden University Medical Centre
Translational Oncologic Imaging Group
Institute of Nutritional Medicine, TUM
Department of Neuroradiology, TUM
Chair for Biological Imaging, TUM
Chair of Molecular Nutrition, TUM
Department of Surgery, TUM
Department of Nuclear Medicine, TUM
Department of Computer Science, TUM
Chair of Food and Bioprocess Engineering, TUM
Chair of Analytical Food Chemistry, TUM
- TUM/Imperial College Joint Academy of Doctoral Studies
- European Research Council (ERC) Proof of Concept Grant
- German Academic Exchange Service (DAAD) University Partnership with Greece
- TUM Global Incentive Fund
- German Research Foundation (DFG) SFB 824, Imaging for the selection, monitoring and individualization of cancer therapies
- European Research Council (ERC) Starting Grant
- TUM August Wilhem Scheer Visiting Professorship
- German Society for Muscle Diseases
- Wilhelm und Else-Heraus Stiftung
- Philips Healthcare
D. Weidlich, M. Zamskiy, M. Maeder, S. Ruschke, S. Marburg, D. C. Karampinos, Reduction of vibration-induced signal loss by matching mechanical vibrational states: Application in high b-value diffusion-weighted MRS, Magnetic Resonance in Medicine, 84:39–51, 2020
D. Franz, M. N. Diefenbach, F. Treibel, D. Weidlich, J. Syväri, S. Ruschke, M. Wu, C. Holzapfel, T. Drabsch, T. Baum, H. Eggers, E. J. Rummeny, H. Hauner, D. C. Karampinos, Differentiating supraclavicular from gluteal adipose tissue based on simultaneous PDFF and T2* mapping using a 20-echo gradient-echo acquisition, Journal of Magnetic Resonance Imaging, 50:424, 2019
D. Weidlich, J. Honecker, O. Gmach, M. Wu, R. Burgkart, S. Ruschke, D. Franz, B. H. Menze, T. Skurk, H. Hauner, U. Kulozik, D. C. Karampinos, Measuring large lipid droplet sizes by probing restricted lipid diffusion effects with diffusion-weighted MRS at 3T, Magnetic Resonance in Medicine, 81:3427, 2019
M. N. Diefenbach, J. Meineke, S. Ruschke, T. Baum, A. Gersing, D. C. Karampinos, On the sensitivity of quantitative susceptibility mapping for measuring trabecular bone density, Magnetic Resonance in Medicine, 81:1793, 2019
M. N. Diefenbach, S. Ruschke, H. Eggers, J. Meineke, E. J. Rummeny, D. C Karampinos, Improving chemical shift encoding-based water–fat separation based on a detailed consideration of magnetic field contributions, Magnetic Resonance in Medicine, 80:990, 2018
B. Cervantes, A. T. Van, D. Weidlich, H. Kooijman, A. Hock, E. J. Rummeny, MD, A. Gersing, J. S. Kirschke, D. C Karampinos, Isotropic resolution DTI of lower back nerves using a phase-corrected diffusion-prepared 3D TSE, Magnetic Resonance in Medicine, 80:609, 2018
D. Franz, D. Weidlich, F. Freitag, C. Holzapfel, T. Drabsch, T. Baum, H. Eggers, A. Witte, E. J. Rummeny, H. Hauner, D. C. Karampinos, Association of proton density fat fraction in adipose tissue with imaging-based and anthropometric obesity markers in adults, Nature International Journal of Obesity, 42:175, 2018
D. C. Karampinos, S. Ruschke, M. Dieckmeyer, M. Diefenbach, D. Franz, A. S. Gersing, R. Krug, T. Baum, Quantitative MRI and spectroscopy of bone marrow, Journal of Magnetic Resonance Imaging, 47:332, 2018
M. Dieckmeyer, S. Ruschke, H. Eggers, H. Kooijman, E. J. Rummeny, J. S. Kirschke, T. Baum, D. C. Karampinos, ADC quantification of the vertebral bone marrow water component: removing the confounding effect of residual fat, Magnetic Resonance in Medicine, 78:1432, 2017
S. Ruschke, H. Eggers, H. Kooijman, M. N. Diefenbach, T. Baum, A. Haase, E. J. Rummeny, H. H. Hu, D. C. Karampinos, Correction of phase errors in quantitative water−fat imaging using a monopolar time-interleaved multi-echo gradient echo sequence, Magnetic Resonance in Medicine, 78:984, 2017