X-ray and CT Research
Main Research Activities
Spectral and Dual-Energy Computed Tomography
Photon Counting Computed Tomography
X-ray Imaging with brilliant X-ray sources MUCLS
Dark-field X-ray Imaging
Dark-field CT Imaging
Prof. Dr. Pfeiffer is an attending at the Institute of Diagnostic and Interventional Radiology and the PI of the X-Ray and CT Research Group. Her main interests and most important scientific results lie in the field of photon counting CT technology, dual-energy and spectral CT applications, dark-field and phase contrast imaging, and machine learning in clinical applications. Prof. Dr. Pfeiffer is internationally well recognized and has strong collaborations with several highly-recognized institutions, such as the Massachusetts General Hospital / Harvard Medical School. She is a member of the scientific research committee of the Radiological Society of North America (RSNA). Her research achievements have been awarded with the prestigious Röntgen-Prize.
Senior Scientists
Dr. Alexander Fingerle, MD, MHBA
Dr. Andreas Sauter, MD
Dr. Lorenz Birnbacher, PhD
Research Fellows
Dr. Isabelle Riederer, MD
Jannis Bodden
Dr. Dominik Deniffel, MD
Dr. Florian Gassert
PhD, MD & MSc Students
Stefanie Beck (MD student)
Eva Braig, MSc (PhD student)
Antonia Kössinger (MD student)
Stephanie Kulpe, MSc (PhD student)
Marie Lodde (MD student)
Manuel Schultheiß, MSc (PhD student)
Anna-Lena Zaschka (MD student)
Sophia Ostmeier (MD student)
Laurenz Jahn (MD Student)
Yagubbayli Farid (Master Student)
Aybar Burak (Master Student)
Lochschmidt Maximilian (Master Student)
Local Collaborators
Daniel Cremers, Faculty of Informatics, Technical University of Munich, Germany
Julia Herzen, Chair for Biomedical Physics & Munich School of BioEngineering, Technical University of Munich, Germany
Tobias Lasser, Faculty of Informatics, Technical University of Munich, Germany
Karl-Ludwig Laugwitz, Department of Cardiology, Technical University of Munich, Germany
Franz Pfeiffer, Chair for Biomedical Physics & Munich School of BioEngineering, Technical University of Munich, Germany
Munich School of BioEngineering
International Collaborators
Philippe Douek, Claude Bernard University Lyon, Lyon, France.
Anushri Parakh, Massachusetts General Hospital, Harvard University, Boston, United States.
Dushyant Sahani, University of Washington, United States, Seattle, United States.
David Maintz, University of Cologne, Colone, Germany
Philips Healthcare
Braig, E.M., Roiser, N., Kimm, M.A., Busse, M., Andrejewski, J., Scholz, J., Petrich, C., Gustschin, A., Sauter, A., Bodden, J., Meurer, F., Korbel, R., Pfeiffer, F., Herzen, J. & Pfeiffer, D. (2020) X-ray Dark-Field Radiography: Potential for Visualization of Monosodium Urate Deposition. Invest Radiol.
Sauter, A.P., Ostmeier, S., Nadjiri, J., Deniffel, D., Rummeny, E.J. & Pfeiffer, D. (2020) Iodine concentration of healthy lymph nodes of neck, axilla, and groin in dual-energy computed tomography. Acta Radiol, 284185120903448.
Scherer, K., Hammel, J., Sellerer, T., Mechlem, K., Renger, B., Bähr, A., Kupatt, C., Hinkel, R., Herzen, J., Pfeiffer, F., Rummeny, E. & Pfeiffer, D. (2019) Dynamic Quantitative Iodine Myocardial Perfusion Imaging with Dual-Layer CT using a Porcine Model. Sci Rep, 9, 16046.
Riederer, I., Si-Mohamed, S., Ehn, S., Bar-Ness, D., Noël, P.B., Fingerle, A.A., Pfeiffer, F., Rummeny, E.J., Douek, P. & Pfeiffer, D. (2019) Differentiation between blood and iodine in a bovine brain-Initial experience with Spectral Photon-Counting Computed Tomography (SPCCT). PLoS One, 14, e0212679.
Riederer, I., Bar-Ness, D., Kimm, M.A., Si-Mohamed, S., Noël, P.B., Rummeny, E.J., Douek, P. & Pfeiffer, D. (2019) Liquid Embolic Agents in Spectral X-Ray Photon-Counting Computed Tomography using Tantalum K-Edge Imaging. Sci Rep, 9, 5268.
Kulpe, S., Dierolf, M., Günther, B., Busse, M., Achterhold, K., Gleich, B., Herzen, J., Rummeny, E., Pfeiffer, F. & Pfeiffer, D. (2019) K-edge Subtraction Computed Tomography with a Compact Synchrotron X-ray Source. Sci Rep, 9, 13332.
Deniffel, D., Sauter, A., Dangelmaier, J., Fingerle, A., Rummeny, E.J. & Pfeiffer, D. (2019) Differentiating intrapulmonary metastases from different primary tumors via quantitative dual-energy CT based iodine concentration and conventional CT attenuation. Eur J Radiol, 111, 6-13.
Pfeiffer, D., Parakh, A., Patino, M., Kambadakone, A., Rummeny, E.J. & Sahani, D.V. (2018) Iodine material density images in dual-energy CT: quantification of contrast uptake and washout in HCC. Abdom Radiol (NY), 43, 3317-3323.
Riederer, I., Fingerle, A.A., Baum, T., Kirschke, J.S., Rummeny, E.J., Noël, P.B. & Pfeiffer, D. (2018) Acute infarction after mechanical thrombectomy is better delineable in virtual non-contrast compared to conventional images using a dual-layer spectral CT. Sci Rep, 8, 9329.
Muenzel, D., Bar-Ness, D., Roessl, E., Blevis, I., Bartels, M., Fingerle, A.A., Ruschke, S., Coulon, P., Daerr, H., Kopp, F.K., Brendel, B., Thran, A., Rokni, M., Herzen, J., Boussel, L., Pfeiffer, F., Proksa, R., Rummeny, E.J., Douek, P. & Noël, P.B. (2017) Spectral Photon-counting CT: Initial Experience with Dual-Contrast Agent K-Edge Colonography. Radiology, 283, 723-728.